| February |
| | 20 | 10:00AM | Missouri Valley | vs. | Rogers State | 1-5 | |
| | Cow Town Classic Tournament, Ft. Worth, TX | |
| | | 1:00PM | Missouri Valley | vs. | Univ of Science and Arts of Oklahoma | 2-10 | |
| | Cow Town Classic Tournament, Ft. Worth, TX | |
| | | 3:00PM | Missouri Valley | vs. | Northwestern Oklahoma State University | 3-6 | |
| | Cow Town Classic Tournament, Ft. Worth, TX | |
| | 21 | | Missouri Valley | vs. | York College | 5-3 | |
| | Cow Town Classic Tournament, Ft. Worth Tx | |
| | | | Missouri Valley | vs. | Houston-Victoria | 1-12 | |
| | Cow Town Classic Tournament, Ft. Worth, TX | |
| | | | Missouri Valley | vs. | Northwood University | 2-0 | |
| | Cow Town Classic Tournament, Ft. Worth, TX | |
| | | | Missouri Valley | vs. | Northwestern Oklahoma State University | 1-2 | |
| | Cow Town Classic Tournament, Ft. Worth, TX | |
| | 24 | 2:00PM | Ottawa University | @ | Missouri Valley | 3-9 | |
| | | Game 2 | Ottawa University | @ | Missouri Valley | 0-4 | |
| | 27 | 10:00AM | Missouri Valley | vs. | Calumet College of St. Joseph | 14-5 | |
| | Evangel University Early Bird Tournament, Springfield, MO | |
| | | 1:30PM | Missouri Valley | vs. | William Woods University | 9-5 | |
| | Evangel University Early Bird Tournament, Springfield, MO | |
| | | 3:15PM | Missouri Valley | vs. | Rogers State | 4-3 | |
| | Evangel Unviersity Early Bird Tournament, Springfield, MO | |
| | 28 | 11:45AM | Missouri Valley | vs. | Williams Baptist College | RAIN | |
| | Evangel Unviersity Early Bird Tournament, Springfield, MO | |
| March |
| | 6 | 1:00PM | Park University | @ | Missouri Valley | 7-0 | |
| | | Game 2 | Park University | @ | Missouri Valley | 2-1 | |
| | 15 | 9:00AM | Missouri Valley | vs. | Cardinal Stritch University | 5-1 | |
| | Tucson Invitational Games, Tucson, AZ | |
| | | 11:00AM | Lubbock Christian | vs. | Missouri Valley | 7-2 | |
| | Tucson Invitational Games, Tucson, AZ | |
| | 16 | 4:30PM | York College | vs. | Missouri Valley | 0-8 | |
| | Tucson Invitational | |
| | | 7:00PM | Minot State University | vs. | Missouri Valley | 5-3 | |
| | Tucson Invitational Games, Tucson, AZ | |
| | 17 | 4:30PM | Huntington University | vs. | Missouri Valley | 3-2 | (8) |
| | Tucson Invitational Games, Tucson, AZ | |
| | | 7:00PM | Trinity Christian College | vs. | Missouri Valley | 1-11 | |
| | Tucson Invitational Games, Tucson, AZ | |
| | 19 | 10:00AM | Missouri Valley | vs. | Wesleyan College | 3-4 | |
| | Tucson Invitational Games, Tucson, AZ | |
| | | 12:00PM | Hastings College | vs. | Missouri Valley | 1-2 | |
| | Tucson Invitational Games, Tucson, AZ | |
| | | 2:30PM | Cardinal Stritch University | vs. | Missouri Valley | 1-4 | |
| | Tucson Invitational Games, Tucson, AZ | |
| | 20 | 2:30PM | Dickinson State University | vs. | Missouri Valley | 2-4 | |
| | Tucson Invitational Games, Tucson, AZ | |
| | | 5:00PM | California Baptist University | vs. | Missouri Valley | 8-3 | |
| | Tucson Invitational Games, Tucson, AZ | |
| | 21 | 2:30PM | Taylor University | vs. | Missouri Valley | 4-8 | |
| | Tucson Invitational Games, Tucson, AZ | |
| | | 5:30PM | California State University-San Marcos | vs. | Missouri Valley | 4-5 | |
| | Tucson Invitational | |
| | 27 | 2:00PM | Missouri Baptist College | @ | Missouri Valley | RAIN | |
| | | Game 2 | Missouri Baptist College | @ | Missouri Valley | RAIN | |
| * | 30 | 2:00PM | Missouri Valley | @ | Central Methodist | 3-2 | |
| | Postponed from March 28 | |
| * | | Game 2 | Missouri Valley | @ | Central Methodist | 2-3 | (8) |
| | Postponed from March 28 | |
| April |
| * | 4 | 1:00PM | Culver-Stockton | @ | Missouri Valley | 1-2 | |
| | MVC wins in the bottom of the 7th | |
| * | | Game 2 | Culver-Stockton | @ | Missouri Valley | 1-3 | |
| * | 7 | 5:00PM | Benedictine | @ | Missouri Valley | 8-10 | |
| * | | Game 2 | Benedictine | @ | Missouri Valley | 5-10 | |
| * | 8 | 3:00PM | Missouri Valley | @ | Evangel | 3-6 | |
| * | | Game 2 | Missouri Valley | @ | Evangel | 1-6 | |
| * | 11 | 2:00PM | MidAmerica Nazarene | @ | Missouri Valley | 2-3 | |
| * | | Game 2 | MidAmerica Nazarene | @ | Missouri Valley | 0-5 | |
| * | 13 | 3:00PM | Missouri Valley | @ | Baker | 2-5 | |
| * | | Game 2 | Missouri Valley | @ | Baker | 5-6 | (9) |
| * | 14 | 3:00PM | Missouri Valley | @ | Avila | 4-1 | |
| * | | Game 2 | Missouri Valley | @ | Avila | 10-11 | |
| * | 15 | 4:00PM | Missouri Valley | @ | Lindenwood University | 0-4 | |
| | Katy Wine pitched a no--hitter | |
| * | | Game 2 | Missouri Valley | @ | Lindenwood University | 10-6 | |
| * | 16 | 2:00PM | Missouri Valley | @ | Graceland | 2-1 | |
| * | | Game 2 | Missouri Valley | @ | Graceland | 2-0 | |
| * | 22 | | William Jewell College | @ | Missouri Valley | 3-1 | (12) |
| * | | Game 2 | William Jewell College | @ | Missouri Valley | 1-6 | |
| | Janie Jungerman pitches a No-Hitter | |
| | 25 | 2:00PM | William Jewell College | @ | Missouri Valley | 1-7 | |
| | HAAC Quarterfinal - Game 1 (best of 3) | |
| | | 4:00PM | William Jewell College | @ | Missouri Valley | 1-8 | |
| | HAAC Quarterfinal - Game 2 (best of 3) | |
| | 28 | 3:00PM | Missouri Valley | @ | Evangel | 2-1 | |
| | HAAC Semifinal - Game 1l (best of 3) | |
| | | 5:00PM | Missouri Valley | @ | Evangel | 4-2 | |
| | HAAC Semifinal - Game 2 (best of 3) | |
| May |
| | 2 | 2:00PM | Missouri Valley | @ | Central Methodist | 3-0 | |
| | HAAC Championship - Game 1 (best of 3) | |
| | | 4:00PM | Missouri Valley | @ | Central Methodist | 0-1 | |
| | HAAC Championship - Game 2 (best of 3) | |
| | 3 | 1:00PM | Missouri Valley | @ | Central Methodist | 3-2 | |
| | Missouri Valley wins HAAC championship series. | |
| | 14 | 2:30PM | Missouri Valley | vs. | Concordia University | 0-1 | |
| | NAIA Softball National Championships | |
| | 15 | 12:30PM | Missouri Valley | vs. | Dickinson State University | 0-5 | |
| | NAIA Softball National Championships | |
| | 17 | 8:00PM | Missouri Valley | vs. | Northwood University | 7-4 | |
| | NAIA Softball National Championships | |
